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Profile

Name: Dr. Elly Munde

Qualifications

  • PhD Medical Genetics, Maseno University, 2018
  • Medical Biotechnology, Maseno University, 2013
  • Biomedical Sciences & Technology Maseno University, 2010

Research Interests

  • Human Infectious disease genetics, Immunology, Molecular Biology and Pharmacology

External Links/Affiliations

  1. https://scholar.google.com/citations?user=EMyAF4AAAAAJ&hl=en
  2. https://www.researchgate.net/profile/Elly-Munde

Publications-    

  1. Kosiyo Paul, Otieno Walter, Gitaka Jesse, Munde Elly O. and Ouma Collins. Association between haematological parameters and sickle cell genotypes in children with Plasmodium falciparum malaria resident in Kisumu County in Western Kenya. BMC Infect Dis 20, 887 (2020). https://doi.org/10.1186/s12879-020-05625-z
  2. Andreína Pacheco, Kristan A. Schneider, Qiuying Cheng, Elly O. Munde, Caroline Ndege, Clinton Onyango, Evans Raballah, Samuel B. Anyona, Collins Ouma, Douglas J. Perkins and Ananias A. Escalante. Changes in the frequencies of Plasmodium falciparum dhps and dhfr drug-resistant mutations in children from Western Kenya from 2005 to 2018: the rise of Pfdhps S436H. Malaria Journal volume 19, Article number: 378 (2020). DOI https://doi.org/10.1186/s12936-020-03454-8
  3. Ahmed JS, Guyah B, Sang' D, Webale MK, Mufyongo NS, Munde E, Ouma C. Influence of blood group, Glucose-6-phosphate dehydrogenase and Haemoglobin genotype on Falciparum malaria in children in Vihiga highland of Western Kenya. BMC Infect Dis. 2020 Jul 9;20(1):487. DOI https://doi.org/10.1186/s12879-020-05216-y . PMID: 32646433; PMCID: PMC7346653.
  4. Laura Nyawira Wangai, Kenny Kimani Kamau, Immaculate Marwa, Elly O Munde, Samuel Mburu, John Mwangi, Mark Webale, Dennis Butto, Lucy Kamau, John Hiuhu. Distribution and Contribution of K13-propeller Gene to Artemisinin Resistance in sub-Saharan Africa: A Systematic Review. Biomedical Sciences. Vol. 6, No. 2, 2020, pp. 38-43. doi: 10.11648/j.bs.20200602.14
  5. Sammy N Kinuthia, Elly O Munde, Evans Odhiambo, Steven Obuya Were, Bernard Guyah and Philip R Aduma. Chemotherapeutic Activities of Selected Medicinal Plant Extracts Used in Management of AIDS-Related Opportunistic Infections in The Lake Victoria Basin of Kenya. Acta Scientific Microbiology (ISSN: 2581-3226). August 2019.  DOI: 10.31080/ASMI.2019.02.0295.  https://actascientific.com/ASMI/pdf/ASMI-02-0295.pdf 
  6. Sabiano O Odero, Lilian Ogonda, David Sang, Elly O Munde, Clement Shiluli, Patrick Chweya. Distribution of Biomphalaria Snails in Associated Vegetations and Schistosome Infection Prevalence Along the Shores of Lake Victoria in Mbita, Kenya.    November, 2019, East African Health Research Journal 2019, 3 (2).  https://doi.org/10.24248/eahrj.v3i2.615
  7. David Omondi Okeyo, Sussy Gumo, Elly O. Munde, Charles O. Opiyo, Zablon O. Omungo, Maureen Olyaro, Rachel K. Ndirangu, Nanlop Ogbureke, Sophie Efange and Collins Ouma.  Socio-demographic and facility-based determinants of perceived quality of nutrition Services of Pregnant and Lactating Adolescent Girls in Trans-Mara east Sub-County, Narok County, Kenya.  BMC Nutrition volume 5, Article number: 48 (2019)
  1. Kisia LE, Kempaiah P, Anyona SB, Munde EO, Achieng AO, Ong'echa JM, Lambert CG, Chelimo K, Ouma C, Perkins DJ, Raballah E Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum. BMC Med Genet. 2019 Aug 16; 20(1):140. doi: 10.1186/s12881-019-0866-z.
  2. Okeyo DO, Gumo S, Munde EO, Opiyo CO, Omungo ZO, Olyaro M, Ndirangu RK, Ogbureke N, Efange S, Ouma C. Nutritional service needs of pregnant and lactating adolescent girls in Trans-Mara East Sub-County, Narok County: focus on access and utilization of nutritional advice and services. BMC Pregnancy Childbirth. 2019 Jul 5;19(1):229. doi: 10.1186/s12884-019-2391-7.
  3. Munde EO, Okeyo WA, Raballah E, Anyona SB, Were T, Ong'echa JM, Perkins DJ, Ouma C. Association between Fcγ receptor IIA, IIIA and IIIB genetic polymorphisms and susceptibility to severe malaria anemia in children in western Kenya. . BMC Infect Dis. 2017 Apr 20;17(1):289. doi: 10.1186/s12879-017-2390-0.
  4. Munde EO, Raballah E, Okeyo WA, Ong'echa JM, Perkins DJ, Ouma C. Haplotype of non-synonymous mutations within IL-23R is associated with susceptibility to severe malaria anemia in a falciparum holoendemic transmission area of Kenya. BMC Infect Dis. 2017 Apr 20;17(1):291. doi: 10.1186/s12879-017-2404-y.
  5. Were T, Wesongah JO, Munde E, Ouma C, Kahiga TM, Ongecha-Owuor F, Kiarie JN, Ahmed AA, Makokha EP, Budambul a V. Clinical chemistry profiles in injection heroin users from Coastal Region, Kenya. BMC Clin Pathol. 2014 Jul 9;14:32. doi: 10.1186/1472-6890-14-32. eCollection 2014.
  6. Okeyo WA, Munde EO, Okumu W, Raballah E, Anyona SB, Vulule JM, Ong'echa JM, Perkins DJ, Ouma C. Interleukin (IL)-13 promoter polymorphisms (-7402 T/G and -4729G/A) condition susceptibility to pediatric severe malarial anemia but not circulating IL-13 levels. BMC Immunol. 2013 Mar 25;14:15. doi: 10.1186/1471-2172-14-15.
  7. Munde EO, Okeyo WA, Anyona SB, Raballah E, Konah S, Okumu W, Ogonda L, Vulule J, Ouma C. Polymorphisms in the Fc gamma receptor IIIA and Toll-like receptor 9 are associated with protection against severe malarial anemia and changes in circulating gamma interferon levels. Infect Immun. 2012 Dec;80(12):4435-43. doi: 10.1128/IAI.00945-12. Epub 2012 Oct 8.

 

Scientific Conferences Papers

  1. Onyango , Munde E.O , Onyango P.O., Perkins D. J. , Ouma C. (2019). Promoter variations in NCR3 condition P. falciparum malaria outcomes in children in western Kenya. Conference: African International Biotechnology and Biomedical Conference, AIBBC 2019
  2. Elly O. Munde, Prakasha Kempaiah, Angela O. Achieng’, Lily Kisia, Evans Raballah, Samuel B. Anyona, Collins Ouma and Douglas J. Perkins Association between genotype combinations of the Nuclear factor B1 (NFKB1) and nuclear factor inhibitor alpha (NFĸBIA) and severe malaria anemia in from western Kenya. The 7th MIM Conference on Malaria 2018 at Centre International de Conferences Abdou Diouf (CICAD), Dakar, Senegal (Oral presentation)
  3. Elly O. Munde, Prakasha Kempaiah, Angela O. Achieng’, Lily Kisia, Evans Raballah, Samuel B. Anyona, Collins Ouma and Douglas J. Perkins. Variations in the CD40 promoter are associated with susceptibility to falciparum-induced severe malaria anemia in Kenyan children.  ASTMH 2017 Poster #1657
  4. Elly O. Munde, Prakasha Kempaiah , Angela L. Omondi, Lily Kisia, Evans O. Raballah, Samuel B. Anyona, Collins Ouma and Douglas J Perkins.. NFκB1 and NFκBIA promoter polymorphisms and susceptibility to pediatric severe malaria anemi (ASTMH Oral presentation 2016). 
  5. Elly O. Munde, Prakasha Kempaiah , Angela L. Omondi, Lily Kisia, Evans O. Raballah, Samuel B. Anyona, Collins Ouma and Douglas J Perkins. Haplotype within NFĸB1 promoter is associated with risk of severe malaria anaemia and changes in levels of circulating IL-17 in children with falciparum malaria.  ASTMH 2015 Poster #1621
  6. Evans Raballah, Elly O. Munde, Prakasha Kempaiah, Samuel B. Anyona, Zachary Karim, Mark Webale, George Orinda, Michael F. Otieno, Frank Onyambu, James B. Hittner, Lilian Ogonda, Douglas J. Perkins and John M. Ong’echa: Circulating immunoglobulin (Ig)-G against MSP1-42 and PfEMP-1 are not associated with pediatric malaria severity in western Kenya: ASTMH Nov 2014, Abstract #1553 Nov 2014.
  7. B Anyona, K Ha, P Kempaiah,Z Karim,E Raballah, E Munde, F. Onyambu, JM Ong’echa, and DJ Perkins: Association between Inducible Heme Oxygenase (HMOX)-1 Gene Variants and Severe Malarial Anemia among Children Resident in a Plasmodium falciparum Holoendemic Region of Western Kenya. ASTMH Nov 2014, Abstract #968 Nov 2014.
  8. Elly O. Munde, Winnie A. Okeyo, Samwel B. Anyona, Evans Raballah, Wilson Okumu, Douglas J. Perkins, John Vulule, Lilian Ogonda and Collins Ouma: Fc gamma receptor IIIA polymorphisms and differential anti-malarial IgG response in children with severe malaria anemia: 1st Africa International Biotechnology & Biomedical Conference and the 8th International Workshop on Approaches to Single-Cell Analysis Nairobi, Kenya 4th September 2014 Abstract # WPX 5
  9. Elly O. Munde, Evans Rabala, Winnie A. Okeyo, Caroline A. Owaade, Samwel B. Anyona, Wilson Okumu, John M. Vulule, John m. Ongecha, Douglas J. Perkins and Collins Ouma. A variant within the CD14 Promoter (-159C/T) is associated with increased susceptibility to pediatric malarial anemia in a holoendemic Plasmodium falciparum transmission area. The 6th MIM Pan-African Malaria Conference, October 2013 Durban, South Africa.
  10. Winnie A. Okeyo, Elly O. Munde, Evans Rabala, Samwel B. Anyona, Wilson Okumu, John M. Vulule, John m. Ongecha, Douglas J. Perkins and Collins Ouma. Polymorphisms within the Interleukin-23 receptor (IL-23R) exon are associated with susceptibility to pediatric severe malaria anemia in western Kenya.  6th MIM Pan-African Malaria Conference, October 2013.
  11. Wilson Okumu, Winnie A. Okeyo, Elly O. Munde, Evans Raballah, Samwel B. Anyona and Collins Ouma. Evaluation of saliva derived genomic DNA using OMNIgene®.DISCOVER in detection of malaria and human single nucleotide polymorphisms genotyping. 6th MIM Pan-African Malaria Conference, October 2013.
  12. Elly O. Munde, Winnie A. Okeyo, Sussy K. Gumo, Lilian Ogonda, Wilson Okumu, George Orinda and Collins Ouma. Variants within the FcγRIIIA-176A/C and Tolllike receptor (TLR)-9 (-1237T/C) gene promoter is associated with increased susceptibility to pediatric severe malarial anemia and circulating interferon gamma. ASTMH Nov 2012, Abstract #1183.
  13. Winnie A. Okeyo, Elly O. Munde, Carren A. Watsiera, Wilson Okumu, George Orinda and Collins Ouma. Variation within the Interleukin-13 (-7402T/G and -4729G/A) is associated with susceptibility to pediatric severe malaria anemia and functional changes in circulating IL-13. ASTMH Nov 2012, Abstract #1184